Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Calcium (from tricalcium phosphate and calcium stearate in Serratericā„¢)
29 mg
2%
Serrapeptase Enzyme (from Serratio sp.)
40,000 SPU**
†
Nattokinase (from fibrinase enzyme)
2,000 FU***
†

Top Medical Research Studies

8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More

Most Useful Reviews

7.5
Maintains cholesterol levels
It helps to keep my cholesterol levels normal. I'm gradually losing weight as well. All is well!
Read More
7.5
Cholesterol reduction.
6 people found this helpful
This product is very effective! I bought it to reduce cholesterol and normalise vascular patency. Although I have been taking it for just a few weeks, I've already seen results; my blood pressure decreased from a stable 140-145 to 132-134. I will continue taking it and recommend it, especially when consumed on an empty stomach.
Read More
7.5
Improved cholesterol levels
1 people found this helpful
I have taken this for at least two years. My cholesterol levels improved dramatically during my first annual medical check, which was six months after I began using natto-serra.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 8 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Maintains cholesterol levels
It helps to keep my cholesterol levels normal. I'm gradually losing weight as well. All is well!
Read More
7.5
Cholesterol reduction.
6 people found this helpful
This product is very effective! I bought it to reduce cholesterol and normalise vascular patency. Although I have been taking it for just a few weeks, I've already seen results; my blood pressure decreased from a stable 140-145 to 132-134. I will continue taking it and recommend it, especially when consumed on an empty stomach.
Read More
7.5
Improved cholesterol levels
1 people found this helpful
I have taken this for at least two years. My cholesterol levels improved dramatically during my first annual medical check, which was six months after I began using natto-serra.
Read More
6
Lowers cholesterol levels
1 people found this helpful
It can effectively lower triglyceride cholesterol, but it contains soybean ingredients and may not be suitable for individuals with poor digestion, particularly those prone to diarrhoea.
Read More
7.5
Reduces bad cholesterol
I've been taking it for three weeks, and the dietary supplement effectively thins my blood and lowers my bad cholesterol levels.
Read More

Frequently Asked Questions

7.5
Cholesterol reduction.
6 people found this helpful
This product is very effective! I bought it to reduce cholesterol and normalise vascular patency. Although I have been taking it for just a few weeks, I've already seen results; my blood pressure decreased from a stable 140-145 to 132-134. I will continue taking it and recommend it, especially when consumed on an empty stomach.
7.5
Reduces bad cholesterol
I've been taking it for three weeks, and the dietary supplement effectively thins my blood and lowers my bad cholesterol levels.
7.5
Improved cholesterol levels
1 people found this helpful
I have taken this for at least two years. My cholesterol levels improved dramatically during my first annual medical check, which was six months after I began using natto-serra.
7.5
Maintains cholesterol levels
It helps to keep my cholesterol levels normal. I'm gradually losing weight as well. All is well!
6
Lowers cholesterol levels
1 people found this helpful
It can effectively lower triglyceride cholesterol, but it contains soybean ingredients and may not be suitable for individuals with poor digestion, particularly those prone to diarrhoea.
6
Effective for cholesterol
Hope it aids my cholesterol levels. The pills are an ideal size and have no unpleasant taste. The ingredients are claimed to assist in reducing cholesterol. I consider the quality to be quite good. I haven’t experienced any notable feelings after taking it. I hope it proves effective.
8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.

References

  1. Liu X, Zeng X, Mahe J, Guo K, He P, et al. The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023;15. 10.3390/nu15194239
  2. Yoo HJ, Kim M, Kim M, Lee A, Jin C, et al. The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food Funct. 2019;10:2888. 10.1039/c8fo02324g
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